STATE OF THE GASTROINTESTINAL TRACT IN CHILDREN WITH NEW CORONAVIRUS INFECTION AND CYTOKINE STATUS. IS THERE A RELATIONSHIP?

The article discusses the frequency of gastrointestinal manifestations in children with a new coronavirus infection and their relationship with the level of cytokines in diff erent course of the disease. A total of 161 children aged 3 to 15 years with Covid-19 infection, diagnosed using a PCR smear from the oropharyngeal mucosa, were examined. All had daily noted the presence or absence of gastroenterological symptoms. In all examined, the level of interleukins IL-6, IL-18, IL-10 and procalcitonin in blood serum was determined by enzyme linked immunosorbent assay; sampling was carried out on the fi rst day of hospitalization, before the start of treatment and after 7 days.