Children's medicine of the North-West

Comparative assessment of breast milk components depending on the stage of lactation in women after premature and full-term labour

  • Svetlana E. Pavlova Saint Petersburg State Pediatric Medical University, 2 Lithuania, Saint Petersburg 194100, Russian Federation https://orcid.org/0000-0001-5423-0950
  • Larisa A. Fedorova Saint Petersburg State Pediatric Medical University, 2 Lithuania, Saint Petersburg 194100, Russian Federation
  • Anna А. Fomenko Saint Petersburg State Pediatric Medical University, 2 Lithuania, Saint Petersburg 194100, Russian Federation
  • Valeria P. Novikova Saint Petersburg State Pediatric Medical University, 2 Lithuania, Saint Petersburg 194100, Russian Federation
  • Galina N. Chumakova Saint Petersburg State Pediatric Medical University, 2 Lithuania, Saint Petersburg 194100, Russian Federation
  • Aleksandra S. Panchenko Saint Petersburg State Pediatric Medical University, 2 Lithuania, Saint Petersburg 194100, Russian Federation
  • Elena V. Bem Saint Petersburg State Pediatric Medical University, 2 Lithuania, Saint Petersburg 194100, Russian Federation
  • Victoria A. Yakovleva Saint Petersburg State Pediatric Medical University, 2 Lithuania, Saint Petersburg 194100, Russian Federation
  • Marina I. Levadnevа Saint Petersburg State Pediatric Medical University, 2 Lithuania, Saint Petersburg 194100, Russian Federation
  • Ekaterina G. Batotsyrenova Saint Petersburg State Pediatric Medical University, 2 Lithuania, Saint Petersburg 194100, Russian Federation
  • Ilya V. Kukes LLC «ChromsystemsLab». 20, str. 2 Nauchnyy proyezd, Moscow 117246 Russian Federation
  • Timofey D. Lunegov LLC «ChromsystemsLab». 20, str. 2 Nauchnyy proyezd, Moscow 117246 Russian Federation
  • Vadim A. Kashuro Saint Petersburg State Pediatric Medical University, 2 Lithuania, Saint Petersburg 194100, Russian Federation
  • Victoria A. Chuchina LLC «Lumex». 11, liter I, kor. 205, Michailova str., Saint Petersburg 195009 Russian Federation
  • Anatoly I. Khavkin Research Clinical Institute of Childhood of the Ministry of Health of the Moscow Region. 62 Bolshaya Serpukhovskaya str., Moscow 115093 Russian Federation
Keywords:
грудное молоко новорожденные недоношенные дети аминокислоты грудного молока жирные кислоты грудного молока микроэлементы грудного молока breast milk newborns premature babies breast milk amino acids breastmilk fatty acids breastmilk microelements

Abstract

Introduction. The development of modern laboratory technologies makes it possible to determine the individual characteristics of the composition of breast milk (BM) and the nutritional needs of newborns. The purpose of the study. To study the features of the amino acid, fat and trace element profile of BM depending on the stage of lactation and the gestational age of the child. Materials and methods. For analysis, 21 breast milk samples were taken on days 3, 7, and 21 from women who gave birth on time (n=12) and prematurely (n=9). Results. Significant differences in the composition of breast milk in the profile of threonine, tryptophan, and taurine were demonstrated. When studying the composition of fatty acids, the results were characterized by a high content of essential polyunsaturated fatty acids in premature infants from early stages of lactation. Despite the lack of statistically significant differences in our study due to the small sample size, the findings are in line with the trends observed in numerous research studies and literature reviews, which have demonstrated correlations between milk composition and lactation stage, as well as gestational age at delivery. When examining the levels of micronutrients, including essential elements, we observed significant variability in the samples. The assessment of elements such as zinc and manganese revealed a pronounced deficiency in mature milk from women with full-term pregnancies. In two samples, we also found elevated levels of tin and lead. Conclusion. Given the small sample size and the experimental nature of the study, further research is required.

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How to Cite
Comparative assessment of breast milk components depending on the stage of lactation in women after premature and full-term labour. (2025). Children’s Medicine of the North-West, 13(2), 151-166. https://doi.org/10.56871/CmN-W.2025.14.48.014
Issue
Vol. 13 No. 2 (2025)
Section
Original papers
Published
2025-09-16

How to Cite

Comparative assessment of breast milk components depending on the stage of lactation in women after premature and full-term labour. (2025). Children’s Medicine of the North-West, 13(2), 151-166. https://doi.org/10.56871/CmN-W.2025.14.48.014