Features of ultrasound diagnosis of Ladd’s syndrome in older children

ORIGINAL PAPERS

  • Victoria V. Kholostova Pirogov Russian National Research Medical University; Filatov Children’s City Clinical Hospital, Moscow City Health Department
  • Dmitry A. Baranov N.N. Burdenko Voronezh State Medical University https://orcid.org/0000-0002-1300-8672
  • Elena V. Matvienko Belgorod State National Research University https://orcid.org/0000-0002-0609-6889
  • Yury E. Kitsenko I.M. Sechenov First Moscow State Medical University (Sechenov University) https://orcid.org/0000-0002-4415-6141
  • Elena A. Balakireva Belgorod State National Research University https://orcid.org/0000-0002-3919-7045
  • Anatoly I. Khavkin Research Clinical Institute of Childhood, Ministry of Health of the Moscow Region; Belgorod State National Research University https://orcid.org/0000-0001-7308-7280
  • Ivan V. Subbotin Pirogov Russian National Research Medical University; Filatov Children’s City Clinical Hospital, Moscow City Health Department https://orcid.org/0009-0005-0242-6595
  • Namir A. Al-Mashat Pirogov Russian National Research Medical University; Filatov Children’s City Clinical Hospital, Moscow City Health Department https://orcid.org/0000-0002-8050-7244
  • Alexey N. Smirnov Pirogov Russian National Research Medical University; Filatov Children’s City Clinical Hospital, Moscow City Health Department
  • Valentin V. Sytkov Russian University of Medicine; Federal Scientific and Clinical Center for Children and Adolescents of the Federal Medical-Biological Agency of Russia https://orcid.org/0000-0001-6152-5693
Keywords:
Ladd syndrome “whirlpool sign” syndrome children adolescents ultrasound diagnostic синдром Ледда синдром «whirlpool sign» дети подростки ультразвуковая диагностика

Abstract

Introduction.The article presents an analysis of the results of ultrasound examination in older children with Ladd's syndrome. Important technical features of the ultrasound scanning technique for the most accurate detection of the “whirlpool sign” syndrome in older children are described. The sensitivity and specificity of this technique for diagnosing Ladd's syndrome in older children are presented.The aimof the study is to optimise ultrasound diagnosis of Ladd's syndrome in older children.Materials and methods.A retrospective study was conducted involving 51 older patients with verified Ladd's syndrome. All patients underwent an ultrasound examination according to a developed algorithm, which provided for the start of scanning in the epigastric region, followed by dynamic movement of the sensor in the craniocaudal direction to the left iliac region to assess the course of the mesenteric vessels throughout. The diagnosis was established in the presence of at least one primary criterion (spiral course of the small intestine or mesenteric vessels) and at least two secondary criteria (mesenteric vein dilatation, lymph node enlargement, mesenteric thickening, duodenal dilatation, pendulum-like peristalsis).Results.The developed ultrasound examination algorithm was applied to 35 (68.2%) children over one year of age and allowed verification of Ladd's syndrome in all cases, whereas the standard scanning technique proved uninformative in 29 (56%) patients in the same cohort. The method demonstrated a sensitivity of 75.5% and a specificity of 91.8%. High specificity provides a prognostic value of a positive result at the level of 95%, which makes the method highly reliable for confirming the diagnosis.Conclusion.The proposed specialised ultrasound examination algorithm is a highly effective tool for diagnosing Ladd's syndrome in older children, which significantly improves diagnostic accuracy and minimises the number of false-negative results. Its implementation in clinical practice may solve the problem of late diagnosis of this pathology.

Author Biographies

Victoria V. Kholostova, Pirogov Russian National Research Medical University; Filatov Children’s City Clinical Hospital, Moscow City Health Department

Dr. Sci. (Med.),Associate Professor of the Department of Pediatric Surgery named after Academician Yu.F. Isakov PF N.I. Pirogov Russian State Medical University; pediatric surgeon of the Department of Emergency and Purulent Surgery of the N.F. Filatov Children’s City Clinical Hospital

Dmitry A. Baranov, N.N. Burdenko Voronezh State Medical University

Cand. Sci. (Med.), Associate Professor of the Department of Pediatric Surgery

Elena V. Matvienko, Belgorod State National Research University

Cand. Sci. (Med.), Associate Professor of the Department of Pediatrics

Yury E. Kitsenko, I.M. Sechenov First Moscow State Medical University (Sechenov University)

Cand. Sci. (Med.),Associate Professor, Department of Faculty Surgery No. 1

Elena A. Balakireva, Belgorod State National Research University

Dr. Sci. (Med.), Associate Professor, Head of the Department of Pediatrics

Anatoly I. Khavkin, Research Clinical Institute of Childhood, Ministry of Health of the Moscow Region; Belgorod State National Research University

Dr. Sci. (Med.), Professor, Head of the Department of Gastroenterology and Dietetics named after A.V. Mazurin, Research Clinical Institute of Childhood, Ministry of Health of the Moscow Region;
Professor, Department of Pediatrics with a Course in Pediatric Surgical Diseases, Institute of Medicine, Belgorod National Research University

Ivan V. Subbotin, Pirogov Russian National Research Medical University; Filatov Children’s City Clinical Hospital, Moscow City Health Department

pediatric surgeon of the Department of Emergency and Purulent Surgery of the N.F. Filatov Children’s City Clinical Hospital

Namir A. Al-Mashat, Pirogov Russian National Research Medical University; Filatov Children’s City Clinical Hospital, Moscow City Health Department

Cand. Sci. (Med.),Associate Professor of the Department of Pediatric Surgery named after Academician Yu.F. Isakov Faculty of Pediatrics N.I. PirogovRussian State Medical University

Alexey N. Smirnov, Pirogov Russian National Research Medical University; Filatov Children’s City Clinical Hospital, Moscow City Health Department

Dr. Sci. (Med.),Professor of the Department of Pediatric Surgery named after Academician Yu.F. Isakov Faculty of Pediatrics N.I. Pirogov Russian State Medical University; Head of the Department of Emergency and Purulent Surgery of the N.F. Filatov Children’s City
Clinical Hospital

Valentin V. Sytkov, Russian University of Medicine; Federal Scientific and Clinical Center for Children and Adolescents of the Federal Medical-Biological Agency of Russia

Cand. Sci. (Med.), Associate Professor of the Department of Pediatric Surgery

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